A current novel perspective approach for coronavirus disease-2019 pandemic outbreak.

Coronavirus disease-2019 is a serious health threat around the globe. Across the world, approximately 142 million people were infected, and three million deaths happened. The fast propagation is also associated with constant anxiety, mental stress, and discomfort in public and health-care professionals. Lack of approved drugs regimen to combat the pandemic challenge concretely is a challenging project for all who are committed to developing remedial assistance. However, the successful development of three vaccines gives a solid roadmap to combat this disease. In this review, we highlighted the current development and challenges of this pandemic.

Application of the health Belief Model to assess community preventive practices against COVID-19 in Saudi Arabia.

BACKGROUND: The novel coronavirus disease (COVID-19) has affected hundreds of thousands of people across more than 200 countries. As the pandemic continues, the health agencies, worldwide, are recommending strict preventive practices to avert its transmission at community scale. We sought to predict the behavior of the Saudi population for adopting community preventive practices during the COVID-19 pandemic. METHODS: An online questionnaire consisting of 22 items pertaining to the Health Belief Model constructs was used to measure the perceived susceptibility and perceived severity of contracting COVID-19, along with the perceived benefits and perceived barriers to follow the Ministry of Health's recommendations. The outcome was assessed by their readiness to be compliant with the community protective measures. Data were analyzed using STATA at significance level of 0.05. RESULTS: A total of 900 individuals received the online survey link, of which 688 (response rate: 76.4%) respondents consented to participate in the study. The mean age of the respondents was 31.39 (SD = 8.94). Positive associations were observed between perceived susceptibility (Beta: 0.24; p value < 0.001), perceived severity (Beta: 0.16; p value < 0.001), perceived benefits (Beta: 0.41; p value < 0.001), cue to action (Beta: 2.61; p value < 0.001) and the participation in community preventive practices during the pandemic of the COVID-19. CONCLUSIONS: Health belief model's constructs of perceived susceptibility, severity, benefits and cue to action can be adopted to help strengthen COVID-19 limiting behaviors and prevention programs which can delivered through community pharmacies in Saudi Arabia as well as around the world.

Epidemiology, risk, myths, pharmacotherapeutic management and socio economic burden due to novel COVID-19: A recent update

[...]date there is not even a single drug or vaccine that can be used for the effective treatment for this disease. The lung epithelial cells are the primary target of the virus because host cell is the first step of viral infection followed by the fusion with the cell membrane hence it has been reported that human to human transmission of SARS-CoV2 occurs by the binding between the receptor-binding domains of virus spikes with the cell, which has been identified as angiotensin-converting enzyme-2 (ACE2) receptor. The sample should be stored in laboratory for the amplification of the genetic material extracted from the mucus or saliva sample is through a reverse transcription polymerase chain reaction (RT-PCR), which involves the synthesis of a double-stranded (ds) DNA molecule from an RNA. The probes are taken on the initial gene sequence released by the Shanghai Public Health Clinical Centre & School of Public Health, Fudan University, Shanghai, China on Virological.org, and subsequent confirmatory evaluation by other labs. If the test result is positive, it is recommended that the test is repeated for verification [27].